Editor’s Choice

The molecular cross talk of the dystrophin–glycoprotein complex

The proper function of skeletal muscles relies on their ability to process signals derived from motor neurons, contract, and regenerate efficiently after injury, and the dystrophin–glycoprotein complex plays a central role in these processes as a transmembrane platform that anchors the extracellular matrix to the intracellular cytoskeleton and makes muscle fibers more resistant to injury. This scholarly review focuses on the role of the dystrophin–glycoprotein complex complex in neuromuscular junction and skeletal muscle physiology and discusses novel components associated with the complex.

NYAS Editor's Choice

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