Annals of the New York Academy of Sciences

Nutrient Imbalances in Depressive Disorders Possible Brain Mechanisms^a

R. J. WURTMAN

Clinical Research Center and Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge, Massachusetts 02139

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D. O'ROURKE,

D. O'ROURKE

Department of Psychiatry Massachusetts General Hospital Boston, Massachusetts 02114

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J. J. WURTMAN,

J. J. WURTMAN

Clinical Research Center and Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge, Massachusetts 02139

Search for more papers by this author

R. J. WURTMAN,

R. J. WURTMAN

Clinical Research Center and Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge, Massachusetts 02139

Search for more papers by this author

D. O'ROURKE,

D. O'ROURKE

Department of Psychiatry Massachusetts General Hospital Boston, Massachusetts 02114

Search for more papers by this author

J. J. WURTMAN,

J. J. WURTMAN

Clinical Research Center and Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge, Massachusetts 02139

Search for more papers by this author

First published: December 1989

https://doi.org/10.1111/j.1749-6632.1989.tb53234.x

Citations: 17

These studies were supported in part by National Institutes of Health GCRC Grant M-01-RR00088-24 to the Massachusetts Institute of Technology Clinical Research Center.

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REFERENCES

1 Wurtman, R. J. 1989. Carbohydrates and depression. Sci. Am. January: 68–75.
2 Brzezinski, A. & R. J. Wurtman. 1988. The pineal gland: Its possible roles in human reproduction. Obstet. Gynaecol. Surv. 43(4): 197–207.
3 Terman, M., J. S. Terman, F. M. Quitkin, T. B. Cooper, E. S. Lo, J. M. Gorman, J. W. Stewart & P. J. McGrath. 1988. Response of the melatonin cycle to phototherapy for seasonal affective disorder. J. Neural Transm. 72: 147–165.
4 Garattini, S., T. Mennini & R. Saminin. 1987. From fenfluramine racemate to d-fenfluramine: specificity and potency of the effects on the serotoninergic system and food intake. Ann. N. Y. Acad. Sci. 499: 156–166.
5 Wurtman, J. J., R. J. Wurtman, S. Mark, R. Tsay & J. Growdon. 1985. d-Fenfluramine selectively suppresses carbohydrate snacking in obese subjects. Int. J. Eating Disord. 4: 89–99.
6 Rosenthal, N. & M. Heffernan. 1986. Bulimia, carbohydrate craving and depression: A central connection? In Nutrition and the Brain. R. J. Wurtman & J. J. Wurtman, Eds. Vol. 2: 139–166. Raven Press. New York .
7 Young, S. N. 1986. The clinical psychopharmacology of tryptophan. In Nutrition and the Brain. R. J. Wurtman and J. J. Wurtman, Eds. Vol. 2: 89–138. Raven Press. New York .
8 Fernstrom, J. & R. J. Wurtman. 1972. Brain serotonin content: Increase following ingestion of carbohydrate diet. Science 173: 1023–1025.
9 Lieberman, H., J. J. Wurtman & B. Chew. 1986. Changes in mood after carbohydrate consumption may influence snack choices of obese individuals. Am. J. Clin. Nutr. 44: 772–778.
10 Hudson, J., H. Pope, J. J. Wurtman, D. Yurgelun-Todd, S. Mark & N. Rosenthal. 1988. Bulimia in obese individuals: Relationship to normal weight bulimia. J. Nerv. Ment. Dis. 176: 144–152.

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Volume575, Issue1

The Psychobiology of Human Eating Disorders: Preclinical and Clinical Perspectives

December 1989

Pages 75-85

Nutrient Imbalances in Depressive Disorders Possible Brain Mechanisms^a

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Nutrient Imbalances in Depressive Disorders Possible Brain Mechanismsa

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Nutrient Imbalances in Depressive Disorders Possible Brain Mechanisms^a