Sex and Gender Bias in Animal Research and in Clinical Studies of Cancer, Cardiovascular Disease, and Depressiona
JERI ALTNEU SECHZER,
VITA CARULLI RABINOWITZ,
FLORENCE L. DENMARK,
MICHAEL F. McGINN,
BRUCE M. WEEKS,
CARRIE L. WILKENS,
JERI ALTNEU SECHZER
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorVITA CARULLI RABINOWITZ
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authorFLORENCE L. DENMARK
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorMICHAEL F. McGINN
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorBRUCE M. WEEKS
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authorCARRIE L. WILKENS
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authorJERI ALTNEU SECHZER,
VITA CARULLI RABINOWITZ,
FLORENCE L. DENMARK,
MICHAEL F. McGINN,
BRUCE M. WEEKS,
CARRIE L. WILKENS,
JERI ALTNEU SECHZER
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorVITA CARULLI RABINOWITZ
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authorFLORENCE L. DENMARK
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorMICHAEL F. McGINN
Department of Psychology Pace University New York, New York 10038
Search for more papers by this authorBRUCE M. WEEKS
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authorCARRIE L. WILKENS
Department of Psychology Pace University New York, New York 10038
Department of Psychology Hunter College City University of New York New York, New York 10021
Search for more papers by this authora
This work supported by grants from the National Science Foundation (SBE-9121772), the National Institute of Mental Health, and the City University of New York—Women's Research Development Fund (777–268).
REFERENCES
- 1
Steering Committee of the Physician's Health Study Research Group. 1989. Final report from the aspirin component of the ongoing physician's health study.
N. Engl. J. Med. 321 (32): 129–135.
- 2
Manson, J. E.,
M. J. Stampfer,
G. A. Colditz,
W. C. Willett,
B. Rosner,
F. E. Speizer &
C. H. Hennekens.
1991. A prospective study of aspirin use and primary prevention of cardiovascular disease in women.
J. Am. Med. Assoc. 266 (4): 521–527.
- 3
National Cancer Institute, Division of Cancer Prevention and Control. 1991. Annual Cancer Statistics Review: 1973–1988. U. S. Department of Health and Human Services, Public Health Service, National Institutes of Health. U. S. Government Printing Office.
Washington
,
D. C
.
- 4
Rodin, J. &
J. R. Ickovics.
1990. Women's health: Review and research agenda as we approach the 21st century.
Am. Psychol. 45 (9): 1018–1034.
- 5
McBride, A. B.
1987. Position paper. Women's mental health: Agenda for research. In
Women's Mental Health: Agenda for Research. A. Eichler &
D. L. Parron, Eds.: 28–41.
- 6
Abramson, L.
1990. Uncaring women's health care. New York Times
(May 4).
- 7
Palca, J.
1990. Women left out at NIH.
Science
248: 1601–1602.
- 8
U. S. Department of Health and Human Services. 1985. Women's Health: Report of the Public Health Service Task Force on Women's Health Issues. U. S. Government Printing Office,
Washington
,
D. C
.
- 9
National Institutes of Health Notice. (March 27 1987). Inclusion of women in study populations. Pt. 34; 0770000, 1014002.
- 10
New York Times. 1989 (December 18). Inquiry urged on sex bias in health studies.
- 11
Palca, J.
1990. Op. cit.
- 12
NIH Guide for Grants and Contracts. 1991
(February 3). NIH/ADAMHA policy concerning inclusion of women in study populations. p.
1.
- 13
Sechzer, J. A.,
A. Zmitrovich &
F. L. Denmark.
1985. Sex bias in research. “Sex and Gender Bias in Psychological Research,”
Meeting of the Section of Psychology. October 1985. The New York Academy of Sciences.
New York
,
N. Y
.
- 14
Denmark, F. L.,
J. A. Sechzer &
V. C. Rabinowitz.
1992. Gender, sex and culture: Sources of bias in psychology. p.
24. Program of the 100th
Annual Convention of the American Psychological Association.
Washington
,
D. C
.
- 15
Denmark, F. L.
1993. Leadership in science: Gender matters for the 1990's.
Sex Bias in Research: Are Males and Females the Same?”
p.
45. Annual Meeting of the American Association for the Advancement of Science.
Boston
.
- 16
Rabinowitz, V. C.
1993. Sex bias in human research: More questions of generalization.
Sex Bias in Research: Are Males and Females the Same?”
p.
45. Annual Meeting of the American Association for the Advancement of Science.
Boston
.
- 17
Sechzer, J. A.
1993. Sex bias in animal research: A question of generalization.
Sex Bias in Research: Are Males and Females the Same?”
p.
44. Annual Meeting of the American Association for the Advancement of Science.
Boston
.
- 18
Sechzer, J. A.,
F. L. Denmark &
V. C. Rabinowitz.
1993. Gender bias in women's health research. Presented at the conference entitled Recruitment and Retention of Women in Clinical Studies held by the National Institutes of Health—Office of Research on Women's Health in Bethesda, MD. U. S. Department of Health and Human Services. Proceedings in press.
- 19
Longino, H. E.
1994. Personal communication.
- 20
Unger, R. K.
1979. Toward a redefinition of sex and gender.
Am. Psychol. 34 (11): 1085–1094.
- 21
Wenger, N. K.,
L. Speroff &
B. Packard.
1993. Cardiovascular health and disease in women.
N. Engl. J. Med. 329 (4): 247–256.
- 22
Johnson, W. D.,
K. L. Kayser &
P. M. Pedraza.
1984. Angina pectoris and coronary bypass surgery: Patterns of prevalence and recurrence in 3,105 consecutive patients followed up to 11 years.
Am. Heart J. 108 (4): 1190–1197.
- 23
Hung, J.,
B. R. Chaitman,
J. Lam,
J. Lesperance,
G. Dupras,
P. Fines &
M. G. Bourassa.
1984. Noninvasive diagnostic test choices for the evaluation of coronary artery disease in woman: A multivariate comparison of cardiac fluoroscopy, exercise electrocardiography and exercise thallium myocardial perfusion scintigraphy.
J. Am. Coll. Cardiol. 4 (1): 8–22.
- 24
Hannan, E. L.,
H. R. Bernard,
H. C. Kilburn &
J. F. O'Donnell.
1992. Gender differences in mortality rates for coronary bypass surgery.
Am. Heart J. 123 (4, Pt. 1): 855–872.
- 25
Faxon, D. P.,
K. Ghalilli,
A. K. Jacobs,
N. A. Ruocco,
E. M. Christellis,
M. A. Kellett,
T. R. Varrichione &
T. J. Ryan.
1992. The degree of vascularization and outcome after multivessel coronary angioplasty.
Am. Heart J. 123 (4, Pt. 1): 854–859.
- 26
Centers for Disease Control.
1989. Trends in lung cancer incidence—United States, 1973–1986.
Morbidity and Mortality Weekly Report
38: 505–513
(cited by Rodin & Ickovics. Op. cit. p. 1022).
- 27
Milano, G.,
M. C. Etienne,
E. Cassuto-Viguier,
A. Thyss,
J. Santini,
M. Frenay,
N. Renee,
M. Schneider &
F. Demard.
1992. Influence of sex and age on Fluorouracil clearance.
J. Clin. Oncol. 10 (7): 1171–1175.
- 28
Waits, T. M.,
D. H. Johnson,
J. D. Hainsworth,
K. R. Hande,
M. Thomas &
F. A. Grieco.
1992. Prolonged administration of oral etoposide in non-small cell lung cancer: A phase II trial.
J. Clin. Oncol. 10 (2): 292–296.
- 29
Rothblum, E. D.
1983. Sex-role stereotypes and depression in women. In
The Stereotyping of Women: Its Effects on Mental Health. V. Franks &
E. D. Rothblum, Eds.: 83–111. Springer Publishing Co.
New York
.
- 30
Weissman, M. M. &
G. L. Klerman.
1977. Sex differences and the epidemiology of depression.
Arch. Gen. Psychiatr. 34: 98–111.
- 31
Webb, T. E. &
C. A. VanDevere.
Sex differences in the development of depression: A developmental interaction effect.
Sex Roles
12: 91–95.
- 32
Radloff, L.
1975. Sex differences in depression: The effects of occupation and marital status.
Sex Roles
1: 249–265.
- 33
Vredenberg, K.,
L. Krames &
G. L. Flett.
1986. Sex differences in the clinical expression of depression.
Sex Roles
14: 37–49.
- 34
Strickland, B. R.
1988. Sex-related differences in health and illness.
Psychol. Women Q. 12: 381–399.
- 35
Oliver, S. J. &
B. B. Toner.
1990. The influence of gender role typing on the expression of depressive symptoms.
Sex Roles
22: 775–790.
- 36
Fausto-Sterling, A.
1992. Hormones and aggression. In
Myths of Gender. pp.
123–154. Basic Books.
New York
.
- 37
Strickland, B. R.
1988. Op. cit., p.
395.
- 38
Rodin, J. &
J. R. Ickovics.
1990. Op. cit.
- 39
Unger, R. &
M. Crawford.
1992. In
Women and Gender: A Feminist Psychology. p.
577–579. McGraw-Hill.
New York
.
- 40
Strickland, B. R.
1988. Op. cit., p.
394.
- 41
Unger, R. &
M. Crawford.
1992. Op. cit. p.
576.
