Annals of the New York Academy of Sciences
Volume 1040, Issue 1 pp. 515-517

Glomerular Effects of AVT on the In Situ Perfused Trunk Preparation of the Dogfish

ALAN WELLS, 

ALAN WELLS

School of Biology, Gatty Marine Laboratory, University of St. Andrews, St. Andrews, Fife KY16 8LB, Scotland

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W GARY ANDERSON, 

W GARY ANDERSON

School of Biology, Gatty Marine Laboratory, University of St. Andrews, St. Andrews, Fife KY16 8LB, Scotland

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NEIL HAZON, 

Corresponding Author

NEIL HAZON

School of Biology, Gatty Marine Laboratory, University of St. Andrews, St. Andrews, Fife KY16 8LB, Scotland

Address for correspondence: Neil Hazon, School of Biology, Gatty Marine Laboratory, University of St. Andrews, St. Andrews, Fife KY16 8LB, Scotland. Voice: +44-1334-463451; fax: +44-1334-463443. [email protected]Search for more papers by this author
First published: 12 January 2006
https://doi.org/10.1196/annals.1327.107
Citations: 3

Abstract

Abstract: The effects of arginine vasotocin on the pattern of glomerular perfusion in an elasmobranch fish were examined using an in situ perfused renal trunk preparation. A significant antidiuresis was coupled with a marked reduction in the proportion of filtering glomeruli (86%-25%) and an increase in the proportion of perfused but not filtering (10%-53%) and non-perfused glomeruli (4%-22%). However, the reduction in filtering glomeruli was greater than predicted by measurements of urine flow rate and glomerular filtration rate alone, suggesting that alterations in single nephron glomerular filtration rate may occur.