• Issue
    Volume 1527, Issue 1
    1-107
    September 2023

COVER IMAGE

COVER IMAGE
Free Access

Cover Image, Volume 1527, Issue 1

  • First Published: 11 January 2024
Description unavailable

On the cover: The cover image is based on the Original Article “REG1A protects retinal photoreceptors from blue light damage” by Ze-Hua Xu et al., https://doi.org/10.1111/nyas.15045. The image shows immunofluorescence staining of three tiers of neuronal cells in retinal organoid differentiated from human-induced pluripotent stem cells at day 120.

ISSUE INFORMATION

ISSUE INFORMATION
Free Access

Issue Information

  • Pages: 1-3
  • First Published: 20 September 2023

COMMENTARY

COMMENTARY
Open Access

Affordances and curvature preference: The case of real objects and spaces

  • Pages: 14-19
  • First Published: 10 July 2023
Description unavailable

In a recent publication Chuquichambi and colleagues questioned the widespread view that there is a universal human visual preference for curved shapes and lines. Their meta-analysis revealed that curvature preference is common, but not universal and invariant. In re-analyzing their database, we discovered a negative relationship between curvature preference and objects’ “affordances”. We suggest an embodiment perspective to explain why the curvature preference is diminished for objects with rich affordances.

REVIEWS

REVIEW

The melanocortin receptor signaling system and its role in neuroprotection against neurodegeneration: Therapeutic insights

  • Pages: 30-41
  • First Published: 01 August 2023
Description unavailable

The melanocortin signaling system consists of the melanocortin peptides, their distinctive receptors, accessory proteins, and endogenous antagonists, and it has significant roles in different physiological functions. Activation of the melanocortin system improves different functional traits in neurodegenerative diseases. This review aims to discuss the melanocortin receptor signaling system and its role in neuroprotection, as well as its therapeutic potential.

CONCISE REPORT

CONCISE REPORT

Reimagining scientific conferences—a Keystone Symposia report

  • Pages: 49-59
  • First Published: 03 August 2023
Description unavailable

Keystone Symposium hosted the Open Access Keystone eSymposium entitled “Reimagining Scientific Conferences” on November 15 and 16, 2022. This was a first-of-its-kind event to convene conferencing organizations of various sizes and constituencies with leaders in virtual platform technologies and innovators in conference design. The symposium offered an opportunity for attendees to share and reflect on the successes and challenges of virtual and hybrid meetings, envision new strategies to implement these events successfully and sustainably, and determine a viable path forward in a post-pandemic world. View the event On Demand: https://keypoint.keystonesymposia.org/home/reimagining-scientific-conferences.

ORIGINAL ARTICLES

ORIGINAL ARTICLE

REG1A protects retinal photoreceptors from blue light damage

  • Pages: 60-74
  • First Published: 02 August 2023
Description unavailable

This study investigated a mechanism by which blue light leads to photoreceptor death. By observing blue light exposure in retinal organoids (ROs) and photoreceptor cells, we concluded that there could be significant apoptosis of the photoreceptors. We demonstrate that regenerating islet-derived 1 alpha (REG1A) prevents photoreceptors from undergoing this LD-induced apoptosis by increasing expression of the anti-apoptotic gene Bcl2 and downregulating expression of the pro-apoptotic gene Bax, resulting in reduced mitochondrial damage and improved aerobic capacity in photoreceptor cells.

ORIGINAL ARTICLE
Open Access

Dietary intake and occupational status among female youths of Thai Nguyen, Vietnam

  • Pages: 75-83
  • First Published: 28 July 2023
Description unavailable

Adolescence presents a window of opportunity during which action could be taken to correct nutritional imbalances. Yet, we still know too little about nutrition in adolescence, what factors are most determinant in youths’ choices, and how programs could effectively address challenges.

ORIGINAL ARTICLE
Open Access

Locally relevant food-based recommendations could increase iron and calcium intake for adolescent girls in Vietnam

  • Pages: 97-106
  • First Published: 06 July 2023
Description unavailable

Unhealthy eating habits are common among adolescents in Vietnam. We used linear programming to identify problem nutrients, local nutrient sources, and realistic food-based recommendations (FBRs) to improve nutrient intake among girls 16–22 years in Thai Nguyen, Vietnam. We then identified a reduced set of FBRs to prioritize the most critical micronutrient gaps. Calcium and iron targets could not be met in any realistic diet modeling scenario.

CORRIGENDUM

CORRIGENDUM
Free Access

Corrigendum for Ann. N.Y. Acad. Sci. (2022), 1515, 143-154.

  • Pages: 107
  • First Published: 10 August 2023